Abstract The tight correlation between topologically associating domains (TADs) and epigenetic domains in here Drosophila suggests that the epigenome contributes to define TADs.However, it is still unknown whether histone modifications are essential for TAD formation and structure.By either deleting or shifting key regulatory elements needed to est
The role of the PI3K/AKT signalling pathway in the corneal epithelium: recent updates
Abstract Phosphatidylinositol 3 kinase (PI3K)/AKT (also called protein kinase B, PKB) signalling regulates various cellular processes, such as apoptosis, cell proliferation, the cell cycle, protein synthesis, glucose metabolism, and telomere activity.Corneal epithelial cells (CECs) are the outermost cells of the cornea; they maintain good optical p
A Semi-Continuous State-Transition Probability HMM-Based Voice Activity Detector
We introduce an efficient hidden Markov color touch 7/97 model-based voice activity detection (VAD) algorithm with time-variant state-transition probabilities in the underlying Markov chain.The transition probabilities vary in an exponential charge/discharge scheme and are softly merged with state conditional likelihood into a final VAD decision.Wo
Human resource strategies in Greek tourism businesses: Perspectives and challenges
Orientation: Recruitment and selection play a crucial role in the performance of tourism businesses in Greece.This study explores employee perspectives on recruitment and selection practices in two prominent hotels in Greece.Research purpose: This study analysed current recruitment and selection methods silver lining herbs kidney support within the
Detecting Presymptomatic Infection Is Necessary to Forecast Major Epidemics in the Earliest Stages of Infectious Disease Outbreaks.
We assess how presymptomatic infection affects predictability of infectious disease epidemics.We focus on whether or not a major outbreak (i.e.an epidemic that will go on to infect a large number of individuals) can be predicted reliably soon after initial cases of disease have appeared within a population.For emerging epidemics, significant time a